Hynes During the past 30 years, we have witnessed several major transformations in our ability to understand the biology, biochemistry, and structure of the extracellular matrix ECM and its molecular constituents. This collection illustrates the manifold aspects of ECM biology—the diverse roles of ECM proteins, their effects on cells, and their importance in human diseases.
Matrix structure is not static; it is, in fact, very dynamic. Many human diseases arise from mutations in genes encoding ECM proteins as recognized by Victor McKusick, and cell-matrix adhesion and signaling are also affected in many autoimmune diseases.
One of the fundamental concepts in machine learning is the Confusion Matrix. Combined with Cross Validation, it's how we decide which machine learning.
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